Children’s Health

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease. The discovery of the mutation, which weakens the activity of a protein linked to how the immune system fights viruses in the gut, may help
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You hear the noises, but they don’t bother you at all”: Since 2019, the “Pengunaut Trainer” has been preparing children for magnetic resonance imaging (MRI) examinations through role play. The app was developed under the leadership of the University of Duisburg-Essen (UDE) and the Essen University Hospital (UK Essen). It can already be downloaded free
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Researchers in the United States have provided important insights into the antigen-specific cellular response and evolving humoral (antibody) response to messenger RNA- (mRNA) based vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19). Using single-cell profiling technologies and machine learning analyses, the team identified and characterized
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The prevalence of hypertension, diabetes, cardiovascular diseases, and respiratory diseases are high-risk factors for severe coronavirus disease 2019 (COVID-19). COVID-19, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a respiratory disease that has infected more than 195 million people worldwide and caused the deaths of over 4.18 million as of
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Children whose parents regularly smoke or vape marijuana may experience viral respiratory infections, such as the common cold, more frequently than those whose parents do not smoke, according to a study published in the journal Pediatric Research. Researchers from Wake Forest School of Medicine and Children’s Hospital Colorado, USA surveyed 1,491 parents and caregivers who
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People with type 2 diabetes diagnosed during youth have a high risk of developing complications at early ages and have a greater chance of multiple complications within 15 years after diagnosis. The findings are the culmination of a first-of-its-kind trial funded largely by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part
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With the onset of coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), scientists began an intensive effort to develop vaccines against the virus. These efforts were largely fueled by predictions that public health interventions would inevitably cripple the global economy if continued indefinitely. In the United States,
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Canada should anticipate a resurgence of a childhood respiratory virus as COVID-19 physical distancing measures are relaxed, authors warn in CMAJ (Canadian Medical Association Journal). Cases of respiratory syncytial virus (RSV) have risen sharply in Australia and, more recently, the United States as COVID-19 case counts have waned and pandemic public health measures have been
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Gateway for Cancer Research℠ awards grant to the EORTC 1634- Brain Tumour Group (BTG) academic trial in Post-Pubertal Patients with Newly-Diagnosed Medulloblastoma (PersoMed-I). Medulloblastoma is a rare brain tumor. In the US, it affects 550 adults, and in Europe around 450 adults annually, with the majority being young adults. Adolescent and adult medulloblastomas are biologically
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Scientists at St. Jude Children’s Research Hospital are working with colleagues in China to develop better therapy for childhood acute lymphoblastic leukemia (ALL). Results from a large phase 3 noninferiority clinical trial definitively showed that vincristine and dexamethasone pulses can be eliminated in patients with low-risk disease. The findings were published today in The Lancet
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The economic burden of providing special education and training for a child diagnosed with ADHD (attention-deficit/hyperactivity disorder) is estimated to cost the average American family five times as much as a child without ADHD. Such cost considerations force many families to focus on the remission of the condition through prescribed medications. A study in the
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that caused the coronavirus disease 2019 (COVID-19) pandemic, has affected the USA both physically and economically. Typically mild or asymptomatic in children, it has caused sequelae such as the multisystem inflammatory syndrome in children (MIS-C), which may set in after the virus has been cleared
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St. Jude Children’s Research Hospital investigators have demonstrated that comprehensive genomic sequencing of all pediatric cancer patients is feasible and essential to capitalize on the lifesaving potential of precision medicine. Results from the St. Jude Genomes for Kids study appear online today in the journal Cancer Discovery. Whole-genome and whole-exome sequencing of germline DNA were
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Survival rates for adolescents and young adults diagnosed with cancer have varied considerably depending on cancer type. A new study indicates that survival for multiple cancer types in such patients has improved in recent years, but some patients diagnosed with common cancer types still show limited survival improvements. The results are published by Wiley early
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Adolescents who set goals for their future and those with strong parental support are less likely to use e-cigarettes and other tobacco products, according to a study by UPMC Children’s Hospital of Pittsburgh and University of Pittsburgh School of Medicine physician-scientists. The research, published today in the journal Pediatrics, suggests that strategies to prevent youth
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A recent study conducted as a part of the Real-Time Assessment of Community Transmission-2 (REACT-2) program has estimated the seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies among adult populations in England. The research reveals 5.6% seroprevalence during the early second wave of the coronavirus disease 2019 (COVID-19) pandemic. The study is currently
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Most children with a mental health disorder are not receiving services to address their needs–according to a new study from researchers at Simon Fraser University’s Children’s Health Policy Centre. Their research was published this week in the journal Evidence-Based Mental Health. Researchers found that of the one in eight children (12.7 per cent) who experience
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